ABSTRACT
X-linked reticulate pigmentary disorder is an clinically rare hereditary pigmentary abnormal disease with unknown etiology. This paper reports the diagnosis and treatment of a case of X-linked reticular pigmentosis complicated with nystagmus. The main symptoms and signs were nystagmus, most of the skin of body with dark color, and pigmentation spots on the face, arms, chest, back, etc. Pathological results showed hyperkeratosis of the epidermis, hypertrophy of the acanthosis, normal number of melanocytes in the basal layer, and increased number of melanin particles in some areas. A small number of lymphocytes were infiltrated around the superficial vascular layer, and fungal spores were occasionally seen in the horn layer by periodic acid Schiff (PAS) staining, which was consistent with the characteristics of X-linked reticular pigment abnormalities complicated with nystagmus.
ABSTRACT
Bullous pemphigoid is a chronic obstinate dermatological disease. Hormone is the main therapeutic method, but the disease course is rather long, relapse is frequently seen and difficult to be radically cured; many complications may occur such as pulmonary infection, etc. From traditional Chinese medicine (TCM) basic principal points of view "lung governing skin and hair" and "strengthen the body resistance to eliminate pathogenic factors", the author explored the TCM therapy of bullous pemphigoid. By using clearing away lung heat and invigorating lung qi as the main principles supplemented by invigorating spleen and kidney, eliminating phlegm and blood stasis for treatment of such disease, relatively satisfactory therapeutic results were obtained.